Detalhe da pesquisa
1.
Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics.
Cell
; 171(5): 1165-1175.e13, 2017 Nov 16.
Artigo
Inglês
| MEDLINE | ID: mdl-29149605
2.
Structure-based design of bitopic ligands for the µ-opioid receptor.
Nature
; 613(7945): 767-774, 2023 01.
Artigo
Inglês
| MEDLINE | ID: mdl-36450356
3.
Tuakana-teina peer education programme to help Maori elders enhance wellbeing and social connectedness.
BMC Geriatr
; 24(1): 114, 2024 Jan 30.
Artigo
Inglês
| MEDLINE | ID: mdl-38291380
4.
Development of LB244, an Irreversible STING Antagonist.
J Am Chem Soc
; 145(37): 20273-20288, 2023 09 20.
Artigo
Inglês
| MEDLINE | ID: mdl-37695732
5.
Small molecule 1a reduces FMRpolyG-mediated toxicity in in vitro and in vivo models for FMR1 premutation.
Hum Mol Genet
; 30(17): 1632-1648, 2021 08 12.
Artigo
Inglês
| MEDLINE | ID: mdl-34077515
6.
The HCK/BTK inhibitor KIN-8194 is active in MYD88-driven lymphomas and overcomes mutated BTKCys481 ibrutinib resistance.
Blood
; 138(20): 1966-1979, 2021 11 18.
Artigo
Inglês
| MEDLINE | ID: mdl-34132782
7.
Basolateral amygdala corticotropin releasing factor receptor 2 interacts with nonmuscle myosin II to destabilize memory in males.
Neurobiol Learn Mem
; 206: 107865, 2023 Dec.
Artigo
Inglês
| MEDLINE | ID: mdl-37995804
8.
Chemical systems biology reveals mechanisms of glucocorticoid receptor signaling.
Nat Chem Biol
; 17(3): 307-316, 2021 03.
Artigo
Inglês
| MEDLINE | ID: mdl-33510451
9.
DNA-Encoded Library Screening To Inform Design of a Ribonuclease Targeting Chimera (RiboTAC).
J Am Chem Soc
; 144(46): 21096-21102, 2022 11 23.
Artigo
Inglês
| MEDLINE | ID: mdl-36342850
10.
Dual Inhibitors of Main Protease (MPro) and Cathepsin L as Potent Antivirals against SARS-CoV2.
J Am Chem Soc
; 144(46): 21035-21045, 2022 11 23.
Artigo
Inglês
| MEDLINE | ID: mdl-36356199
11.
The XPB Subunit of the TFIIH Complex Plays a Critical Role in HIV-1 Transcription and XPB Inhibition by Spironolactone Prevents HIV-1 Reactivation from Latency.
J Virol
; 95(4)2021 02 15.
Artigo
Inglês
| MEDLINE | ID: mdl-33239456
12.
Discovery of small-molecule enzyme activators by activity-based protein profiling.
Nat Chem Biol
; 16(9): 997-1005, 2020 09.
Artigo
Inglês
| MEDLINE | ID: mdl-32514184
13.
Development of a putative Zn2+-chelating but highly selective MMP-13 inhibitor.
Bioorg Med Chem Lett
; 76: 129014, 2022 11 15.
Artigo
Inglês
| MEDLINE | ID: mdl-36202189
14.
Phase 3 efficacy and safety of abrocitinib in adults with moderate-to-severe atopic dermatitis after switching from dupilumab (JADE EXTEND).
J Am Acad Dermatol
; 87(2): 351-358, 2022 08.
Artigo
Inglês
| MEDLINE | ID: mdl-35439608
15.
Abrocitinib induction, randomized withdrawal, and retreatment in patients with moderate-to-severe atopic dermatitis: Results from the JAK1 Atopic Dermatitis Efficacy and Safety (JADE) REGIMEN phase 3 trial.
J Am Acad Dermatol
; 86(1): 104-112, 2022 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34416294
16.
Precise small-molecule cleavage of an r(CUG) repeat expansion in a myotonic dystrophy mouse model.
Proc Natl Acad Sci U S A
; 116(16): 7799-7804, 2019 04 16.
Artigo
Inglês
| MEDLINE | ID: mdl-30926669
17.
Visualization of ex vivo rabbit olfactory mucosa and foramina with three-dimensional optical coherence tomography.
Lasers Med Sci
; 37(8): 3203-3211, 2022 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-35779115
18.
Reprogramming of Protein-Targeted Small-Molecule Medicines to RNA by Ribonuclease Recruitment.
J Am Chem Soc
; 143(33): 13044-13055, 2021 08 25.
Artigo
Inglês
| MEDLINE | ID: mdl-34387474
19.
Development of novel NEMO-binding domain mimetics for inhibiting IKK/NF-κB activation.
PLoS Biol
; 16(6): e2004663, 2018 06.
Artigo
Inglês
| MEDLINE | ID: mdl-29889904
20.
Willingness to Use Pre-exposure Prophylaxis (PrEP) and Preferences Among Men Who have Sex with Men in Mumbai and Chennai, India: A Discrete Choice Experiment.
AIDS Behav
; 25(10): 3074-3084, 2021 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-33818643